George and Harold have really done it this time . . . they've created a MONSTER! She's faster, stronger, and more evil than anything the world has seen before --she's Wedgie Woman! With the help of her horrible robots and her ravenous robo-claw, Wedgie Woman is on a mission to take over the world, and she'll give a whopping wedgie to anyone who stands in her way --including Captain Underpants. Will Wedgie Woman's wicked ways spell the end for our heroes?

Spanish title: El Capitan Calzoncillos y la furia de la supermujer macroelastica

Jorge y Berto si la han hecho esta vez…Han creado un MONSTRUO! Es la criatura mas rapida, fuerte y diabolica del mundo, la Supermujer Macroelastica. Con la ayuda de sus horripilantes robots y su garra robotica, la Supermujer Macroelastica se aduena del mundo y le da una paliza a cualquiera que se interponga en su camino, incluyendo al Capitan Calzoncillos. Podra la Mujer Macroelastica destruir a nuestros heroes?