Jeremy Thrane seems to have everything. As the long-time boyfriend of the handsome (but deeply closeted) movie star Ted Masterson, he lives rent-free in a beautiful apartment on the top floor of Ted's Manhattan brownstone and has an easy job that gives him plenty of time to read books and write his novel. When an influential gossip columnist overhears Jeremy talking about Ted, Jeremy's perfect world begins to crumble: in just a few hours Ted asks him to leave. Although Ted says he needs to spend more time with his wife and daughter, Jeremy suspects another man is involved.
With little more than his books, his sprawling manuscript, and his fickle little bird Juanita, Jeremy finds that he needs to re-connect with the eccentric family whose love he has taken for granted, and determine which of his friends have his true well-being in mind. In a dizzying world of art galleries, rock clubs, trendy restaurants, casual sex, dry wit, and drier martinis, Jeremy Thrane must finally figure out what it means to grow up and fall in love.